12 July 2023

Touchlight launches its new customer offering of Discovery grade doggybone DNA (dbDNA)

As part of its expanding range of services to support its customers, Touchlight has announced the launch of a Discovery grade dbDNA™ (enzymatic doggybone DNA) offering to support customer candidate screening.

The availability of the Discovery grade offering will enable customers to receive quick and easy access to 0.5 to 1mg RUO grade dbDNA, which can be ready to use in as little as 4 weeks from receipt of template DNA.

This new service line enables a cost-effective means of facilitating customer access to small scale dbDNA production.

Touchlight’s proprietary doggybone DNA (dbDNA™) overcomes the technical challenges associated with efficiently mass-producing plasmid DNA. The patented dbDNA technology produces a minimal, linear, double stranded, covalently closed DNA vector through an enzymatic manufacturing process, which eliminates bacterial sequences.

It is approved in both Europe and the US as a starting material for the production of gene therapies in Phase I and has advantages over plasmid DNA including a strong expression profile and the amplification of complex sequences.


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About Touchlight

Touchlight is a privately-owned CDMO based in London, U.K., focused on the provision of DNA services and manufacture of enzymatically produced doggybone DNA (dbDNA™) to enable the development of genetic medicines. Touchlight provide rapid, enzymatic DNA development and manufacturing for all advanced therapy production, including mRNA, viral and non-viral gene therapy and DNA API. dbDNA is a minimal, linear, covalently closed structure, which eliminates bacterial sequences. Touchlight’s revolutionary enzymatic production platform enables unprecedented speed, scale, and the ability to target genes with a size and complexity that is impossible with current technologies. Clients can be supported from pre-clinical through development and supply, to licencing and tech transfer for use in-house.

For more information please contact:

Karen Fallen, Chief Executive Officer
Robin Bodicoat, Head of Marketing
E: info@touchlight.com
T: +44 20 8481 9200