Satish Muchakayala
The making of DNA
Enabling the genetic medicine revolution with our unique dbDNA™ technology.
How we make DNAPlatform Technology
dbDNA™:
Powering the genetic medicine revolution
Our novel, synthetic DNA vector, “doggybone” or dbDNA™, and its enzymatic production, enable us to make DNA at the speed, scale and purity necessary to support the rapid growth of genetic medicines.
DNA made using enzymes
We are disrupting the decades-old technology of DNA production, moving away from restrictive biological approaches to instead use a synthetic
Our platform technology
Rapid
Enzymatic manufacturing enables multi-gram GMP DNA production in weeks rather than months
Scalable
Manufactured using benchtop equipment with a significantly smaller footprint than fermentation-based production
Mobile
dbDNA™ technology is highly portable and amenable to technology transfer
Optimal vector
dbDNA™ can encode long, complex, unstable sequences, eliminates bacterial sequences, and has a strong expression profile
Addressing a broad market
Our versatile dbDNA™ technology is being applied across the genetic medicine industry.
Our Services
What can we do for you?
We offer a range of services to support development and commercialisation of the next generation of DNA products.
Pre-clinical services
- Catalogue products
- Molecular biology
- Custom research grade
- Toxicology materials
GMP supply
- GMP dbDNA™ (critical starting materials)
- GMP dbDNA™ (drug substance)
- Commercial supply / on-site supply
Development Services
- Analytical development
- Scale up development
- Formulation
- Stability
Our facilities
Headquartered in Hampton
Take a tour of our stunning buildings and state-of-the-art dbDNA™ manufacturing facilities.
View our facilitiesOur programs and partners
Work with us to develop the next generation of DNA products
We are working in collaboration with esteemed partners, to leverage dbDNA™ in areas where it may offer unique or improved therapies or devices.
Find out more
Knowledge Centre
Dr Tommy Duncan
Webinar – Overcoming Plasmid DNA Limitations in Advanced Therapy Manufacturing
Read Article
Dr Lisa Caproni
Molecular Therapy – Safe and stable generation of induced pluripotent stem cells using doggybone DNA vectors
Read Article
Dr Helen Horton
Nature Biopharma Dealmakers: Reshaping the production of DNA-based therapies
Read moreContact us
We'd like to hear from you
For more information on how our dbDNA™ technology could help advance your project, please contact us.
Get in touch