The making of DNA

Enabling the genetic medicine revolution with our unique doggybone DNA (dbDNA™) technology.

How we make DNA
Platform Technology

doggybone DNA:
Powering the genetic medicine revolution

Our novel, synthetic DNA vector, doggybone DNA or dbDNA™, and its enzymatic production, enable us to make DNA at the speed, scale and purity necessary to support the rapid growth of genetic medicines.

Doggybone DNA animation

DNA made using enzymes

We are disrupting the decades-old technology of DNA production, moving away from restrictive biological approaches to instead use a synthetic DNA vector.

Our platform technology
Rapid icon

Enzymatic manufacturing enables multi-gram GMP DNA production in weeks rather than months

Scalable icon

Manufactured using benchtop equipment with a significantly smaller footprint than fermentation-based production

Mobile icon

doggybone DNA technology is highly portable and amenable to technology transfer

Optimal vector icon
Optimal vector

doggybone DNA can encode long, complex, unstable sequences, eliminates bacterial sequences, and has a strong expression profile

Addressing a broad market

Our versatile doggybone DNA (dbDNA) technology is being applied across the genetic medicine industry.

Our Services

What can we do for you?

We offer a range of services to support development and commercialisation of the next generation of DNA products.

Pre-clinical services
Pre-clinical services
  • Catalogue products
  • Molecular biology
  • Custom research grade
  • Toxicology materials
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GMP Supply
GMP supply
  • GMP dbDNA™ (critical starting materials)
  • GMP dbDNA™ (drug substance)
  • Commercial supply / on-site supply
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Development Services
Development Services
  • Analytical development
  • Scale up development
  • Formulation
  • Stability
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Regulatory Support
Regulatory support
  • Regulatory support
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Our facilities

Headquartered in Hampton

Take a tour of our stunning buildings and state-of-the-art DNA manufacturing facilities.

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Our programs and partners

Work with us to develop the next generation of DNA products

We are working in collaboration with esteemed partners, to leverage doggybone DNA in areas where it may offer unique or improved therapies or devices.

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Knowledge Centre

upporting the Clinical Adoption of Enzymatic DNA in Advanced Therapy Manufacturing
Webinar – Supporting the Clinical Adoption of Enzymatic DNA in Advanced Therapy Manufacturing
Read Article
Nature Reviews Chemistry – DNA synthesis technologies to close the gene writing gap
Nature Reviews Chemistry – DNA synthesis technologies to close the gene writing gap
Read more
Enabling better genetic medicines with enzymatic DNA - doggybone DNA
Brochure – Touchlight doggybone DNA
AAV Manufactureing, Overcoming challenges of plasmid DNA. On demand webinar.
Webinar – Overcoming the challenges of plasmid DNA in AAV manufacturing
Read Article
White paper on lentivirus manufacturing
White Paper – The future of Industrial Scale Lentiviral Vector Manufacturing
Read Article
TOPRA article antibiotic resistance
Article – Antibiotics in biopharmaceutical production
Read Article
Knowledge centre
Contact us

We'd like to hear from you

For more information on how our doggybone DNA technology could help advance your project, please contact us.

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